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KMID : 0614619950270040471
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Korean Journal of Gastroenterology
1995 Volume.27 No. 4 p.471 ~ p.474
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A Case Report of Duodenal Bulb Adenocarcinoma
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Abstract
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Adenocarcinoma of the duodenum is rare. The autopsy incidence of duodenal adenocarcinoma is about 0.3%. The second and third portions of the duodenum are the usual sites of adenocarcinoma. Cancer in the duodenal bulb is exceedingly rare. Recently
authors have experienced a case of duodenal adenocarcinoma on bulb with regional lypmph nodes and liver metastasis in a 59-year-old female patient with complaints of nausea, anorexia, epigastric pain, and weight loss. Endoscopic
gasteroduodenoscopy
revealed multiple protruded lesion on anterior aspect of duodenal bulb. Abdominal CT scan showed numerous variable sized round or conglomerated low density mass lesions with target appearance and multiple lympadeno-pathies. Endoscopic biopsy
tissue
from
duodenal mucosa showed invasion by neoplastic glands with large, hyperchromatic nuclei and frequent mitosis. Fine needle aspiration biopsy tissue from the liver showed invasion by neoplastic cell sheets or neoplastic glands with hyperchromatic,
pleomorphic nucleated cells. The tumor cells showed positive reaction to CEA but negative to AFP. So we report a case of duodenal bulb carcinoma with liver metastasis with a brief review of literature. (Korean J Gastroenterol 1995; 27: 471-474)
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